Sio Capital Management 13F annual report

Sio Capital Management is an investment fund managing more than $265 billion ran by Jin Lee. There are currently 43 companies in Mrs. Lee’s portfolio. The largest investments include Labcorp and Teleflex, together worth $73.4 billion.

Limited to 30 biggest holdings

$265 billion Assets Under Management (AUM)

As of 7th August 2024, Sio Capital Management’s top holding is 245,902 shares of Labcorp currently worth over $50 billion and making up 18.9% of the portfolio value. Relative to the number of outstanding shares of Labcorp, Sio Capital Management owns more than approximately 0.1% of the company. In addition, the fund holds 111,078 shares of Teleflex worth $23.4 billion, whose value fell 6.8% in the past six months. The third-largest holding is Zimmer Biomet Inc worth $16.9 billion and the next is Smith & Nephew plc worth $14.4 billion, with 579,619 shares owned.

Currently, Sio Capital Management's portfolio is worth at least $265 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Sio Capital Management

The Sio Capital Management office and employees reside in New York, New York. According to the last 13-F report filed with the SEC, Jin Lee serves as the Chief Compliance Officer at Sio Capital Management.

Recent trades

In the most recent 13F filing, Sio Capital Management revealed that it had opened a new position in Labcorp and bought 245,902 shares worth $50 billion. This means they effectively own approximately 0.1% of the company. Labcorp makes up 27.5% of the fund's Health Care sector allocation and has grown its share price by 3.0% in the past year.

The investment fund also strengthened its position in Teleflex by buying 77,200 additional shares. This makes their stake in Teleflex total 111,078 shares worth $23.4 billion. Teleflex soared 1.9% in the past year.

On the other hand, there are companies that Sio Capital Management is getting rid of from its portfolio. Sio Capital Management closed its position in Laboratory Corporation Of America Holdings on 14th August 2024. It sold the previously owned 225,902 shares for $49.4 billion. Jin Lee also disclosed a decreased stake in Cigna by 0.6%. This leaves the value of the investment at $8.85 billion and 26,786 shares.

One of the smaller hedge funds

The two most similar investment funds to Sio Capital Management are Missouri Trust & Investment Co and Phraction Management. They manage $265 billion and $265 billion respectively.


Jin Lee investment strategy

Sio Capital Management’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 68.7% of the total portfolio value. The fund focuses on investments in the United States as 48.8% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are large-cap stocks. Stocks with a size of more than $10 billion in market cap make up 16% of the total holdings value. On the other hand, small-cap stocks make up 11.6% of the portfolio. The average market cap of the portfolio companies is close to $18 billion.

The complete list of Sio Capital Management trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Labcorp Holdings Inc.
Opened
245,902
$50,043,516,000 18.88%
Laboratory Corporation Of America Holdings
Closed
225,902
$49,350,551,000
Teleflex Incorporated
227.88%
111,078
$23,363,036,000 8.81%
Globus Medical Inc
Closed
393,420
$21,103,049,000
Zimmer Biomet Holdings Inc
109.36%
155,304
$16,855,143,000 6.36%
Smith & Nephew plc
Opened
579,619
$14,362,959,000 5.42%
Madrigal Pharmaceuticals Inc
Closed
51,000
$13,619,040,000
Organon & Co
26.95%
608,096
$12,587,587,000 4.75%
GSK Plc
18.43%
312,000
$12,012,000,000 4.53%
Corbus Pharmaceuticals Hldgs
Opened
225,165
$10,188,716,000 3.84%
Vaxart Inc
Opened
14,764,991
$9,852,678,000 3.72%
Tyra Biosciences Inc
12.05%
600,294
$9,598,701,000 3.62%
Abbott Laboratories
Opened
89,500
$9,299,945,000 3.51%
Medtronic Plc
Closed
105,000
$9,150,750,000
Cigna Group (The)
64.80%
26,786
$8,854,648,000 3.34%
Kenvue Inc
Opened
485,000
$8,817,300,000 3.33%
Disc Medicine Inc
Opened
192,000
$8,653,440,000 3.26%
Embecta Corp
Closed
585,418
$7,768,497,000
Erasca Inc
18.43%
2,874,536
$6,783,905,000 2.56%
Biodesix Inc
Opened
4,347,855
$6,652,218,000 2.51%
Humacyte Inc
Closed
2,000,000
$6,220,000,000
Healthcare Services Group, Inc.
Closed
421,317
$5,258,036,000
Fusion Pharmaceuticals Inc.
Closed
243,035
$5,181,506,000
Scholar Rock Holding Corp
Closed
273,720
$4,861,267,000
Integra Lifesciences Holdings Corp
Closed
137,000
$4,856,650,000
Astria Therapeutics Inc
24.37%
510,267
$4,643,430,000 1.75%
ANI Pharmaceuticals Inc
17.87%
71,740
$4,568,403,000 1.72%
Bausch Plus Lomb Corp
Opened
302,710
$4,395,349,000 1.66%
Pmv Pharmaceuticals Inc
Opened
2,708,408
$4,387,621,000 1.66%
Zymeworks Inc
Opened
491,128
$4,179,499,000 1.58%
Ocular Therapeutix Inc
Closed
383,026
$3,485,537,000
CytomX Therapeutics Inc
Closed
1,598,590
$3,484,926,000
BridgeBio Pharma Inc
38.39%
125,174
$3,170,657,000 1.20%
Apogee Therapeutics Inc
No change
78,000
$3,069,300,000 1.16%
Context Therapeutics Inc
Opened
1,328,352
$2,663,346,000 1.00%
Modular Med Inc
No change
1,539,352
$2,432,176,000 0.92%
Stoke Therapeutics, Inc.
22.26%
175,301
$2,368,317,000 0.89%
Revance Therapeutics Inc
Closed
468,871
$2,306,845,000
Enanta Pharmaceuticals Inc
No change
177,004
$2,295,742,000 0.87%
Third Harmonic Bio Inc
No change
163,363
$2,123,719,000 0.80%
Nuvation Bio Inc
50.00%
668,115
$1,950,896,000 0.74%
Ars Pharmaceuticals Inc
59.37%
217,864
$1,854,023,000 0.70%
Ventyx Biosciences Inc
106.06%
778,924
$1,799,314,000 0.68%
COMPASS Pathways plc
Opened
293,417
$1,772,239,000 0.67%
Arcutis Biotherapeutics Inc
74.90%
159,626
$1,484,522,000 0.56%
X4 Pharmaceuticals, Inc.
30.34%
2,499,800
$1,449,884,000 0.55%
IDEAYA Biosciences, Inc.
Closed
33,007
$1,448,347,000
Ironwood Pharmaceuticals Inc
Closed
149,400
$1,301,274,000
Prelude Therapeutics Inc
No change
320,394
$1,220,701,000 0.46%
Aprea Therapeutics, Inc.
No change
276,603
$1,125,774,000 0.42%
RAPT Therapeutics, Inc.
No change
315,000
$960,750,000 0.36%
Avalo Therapeutics Inc
603.95%
71,458
$891,081,000 0.34%
Foghorn Therapeutics Inc.
No change
121,672
$699,614,000 0.26%
Boundless Bio Inc
13.33%
162,058
$627,164,000 0.24%
Vincerx Pharma Inc
Closed
102,049
$516,368,000
Verastem Inc
Opened
133,412
$397,568,000 0.15%
Nyxoah S A
No change
50,839
$354,348,000 0.13%
Nextcure Inc
No change
130,000
$206,700,000 0.08%
ASLAN Pharmaceuticals Ltd
No change
254,150
$76,245,000 0.03%
No transactions found
Showing first 500 out of 59 holdings